#  Dan Suess (MIT) 

 



####  calendar\_today Date and Time 

 **February 23, 2023** 

 04:15PM - 05:15PM EST 

####  pin\_drop Location 

 **Pfizer Lecture Hall**  



 

 



 

 Title: Chemical Modification of Iron-Sulfur Cofactors

 Abstract: Iron-sulfur proteins are found in all kingdoms of life and carry out some of the most kinetically demanding reactions in the biosphere. In this talk, I will discuss my group’s efforts to understand how the remarkable biological functions of iron-sulfur clusters derive from their unique electronic structures. Foundational to this line of inquiry is the development of methods for manipulating a cluster’s composition, structure, and properties: incorporating spectroscopically useful isotopes in specific metal sites, altering a cluster’s elemental composition and coordination environment, and characterizing substrate-bound states. Examples will be given from both biological and synthetic systems.



 



 

 



 

 

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