#  Professor Eszter Boros (University of Wisconsin-Minnesota) 

 



####  calendar\_today Date and Time 

 **March 4, 2026** 

 04:00PM - 05:30PM EST 

####  pin\_drop Location 

 **MIT**  



 

 



 

Talk title: ***Catch and Release: Harnessing the Chemistry of Radioactive Metal Ions to Develop Next Generation Metal-based Medicines***

Abstract: Coordination chemistry enables us to transform short-lived, radiometal aqua-ions into tools for non-invasive, diagnostic imaging and disease-targeted radiotherapy for cancers. I will discuss our recent efforts in designing next-generation agents by employing rate-tunable, metal-mediated amide bond cleavage (rTMAC) of trivalent, transition-metal ions and metalloids. Specifically, I will describe how mechanistic understanding allows us to harness reactivity for in situ radiometal separation, pharmacokinetic tuning and timed drug-release. Finally, I will demonstrate how we can adapt rTMAC to rare earth metal ions by rational ligand design.



 

 



 

 See also:- [ Harvard/MIT Inorganic Chemistry Seminar ](/seminars/inorganic-chemistry-seminar)
 
 

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