Harvard-Merck Chemical Biology Lectureship

Join the CCB community on Friday, April 10 for a special symposium hosted by Merck & Co. 

  • When: Thursday, April 9, 2020, 4:15pm to 6:15pm
  • Where: Pfizer Lecture Hall

Speakers

  • Professor James Wells, University of California San Francisco: Talk title TBA

How do cell surface proteomes change in health and disease? The Wells Lab addresses this question by applying protein and antibody engineering, mass spectrometry, and site-directed small molecule discovery to understand and disrupt human-disease-associated signalling processes.

A photo of Niyi Fadeyi and Rob Oslund wearing lab coats in a lab

The cell surface proteome—the surfaceome—is the communication and commerce hub of the cell, allowing it to exchange signals and nutrients with the extracellular environment and other cells. Once triggered, cellular receptors ignite internal signaling pathways that alter cell growth, differentiation, metabolic state, and even cell death or senescence. To understand and modulate these interwoven processes, our lab approaches these questions from three complementary angles: (1) The extracellular proteome; (2) New tools for signaling; (3) Drug discovery.

  • Niyi Fadeyi and Rob Oslund, two speakers from Merck Exploratory Science Center  present "Understanding Immune Cell Interactions via Photocatalysis"